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    Seroquel dose should be reduced to one sixth of original dose when co-medicated with a potent CYP3A4 inhibitor (e.g., ketoconazole, itraconazole, indinavir, ritonavir, nefazodone, etc.). When the CYP3A4 inhibitor is discontinued, the dose of Seroquel should be increased by 6-fold [see Clinical Pharmacology (12.3) and Drug Interactions (7.1)].
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    Seroquel can cause drowsiness, increased appetite, dry mouth, weight gain, dizziness (to name some of the side effects.). If the depakote is not working for you and your doctor has recommended Seroquel for you, it may be helpful. As I said, it works differently.
    It can help to manage or mitigate the racing thoughts, obsessive thoughts, suicidal thoughts. Paranoia, hallucinations, psychomotor excitation, delusions. 4.) Seroquel for Sleep: is Quetiapine Fumarate an Effective Sleep Aid? / Insomnia. Use for insomnia anxiety is “off-label” (meaning that it is not strictly approved for use in these cases).
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    Alcohol can suppress the body’s ability to utilize Seroquel effectively. And, drinking alcohol while using Seroquel could exacerbate the typical side effects of the medication. While it is advised that people who take Seroquel not consume alcohol, the effects of using alcohol while taking Seroquel are considered minor.

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